Problem with big data (?) during computation of sequence distances using TraMineR

I am trying to run an optimal matching analysis using TraMineR but it seems that I am encountering an issue with the size of the dataset. I have a big dataset of European countries which contains employment spells. I have more than 57,000 sequences which are 48 units long and consist of 9 distinct states. In order to get an idea of the analysis, here is the head of sequence object employdat.sts:

[1] EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-...  
[2] EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-...  
[3] ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-...  
[4] ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-...  
[5] EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-EF-...  
[6] ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-ST-...

In a shorter SPS format, this reads as follows:

Sequence               
[1] "(EF,48)"              
[2] "(EF,48)"              
[3] "(ST,48)"              
[4] "(ST,36)-(MS,3)-(EF,9)"
[5] "(EF,48)"              
[6] "(ST,24)-(EF,24)"

After passing this sequence object to the seqdist() function, I get the following error message:

employdat.om <- seqdist(employdat.sts, method="OM", sm="CONSTANT", indel=4)    
[>] creating 9x9 substitution-cost matrix using 2 as constant value  
[>] 57160 sequences with 9 distinct events/states  
[>] 12626 distinct sequences  
[>] min/max sequence length: 48/48  
[>] computing distances using OM metric  
Error in .Call(TMR_cstringdistance, as.integer(dseq), as.integer(dim(dseq)),  : negative length vectors are not allowed

Is this error related to the huge number of distinct, long sequences? I am using a x64-machine with 4GB RAM and I have also tried it on a machine with 8-GB RAM which reproduced the error message. Does someone know a way to tackle this error? Besides, analyses for each single country using the same syntax with an index for the country worked well and produced meaningful results.

Solution

I never saw this error code before, but it might well be due to your high number of sequences. There are at least two things you can try to do:

use the argument "full.matrix=FALSE" in seqdist (see help page). It will compute only the lower triangular matrix and return a "dist" object that can be used directly in the hclust function.
You can aggregate identical sequences (you only have 12626 distinct sequences instead of 57160 sequences), compute the distances, cluster the sequences using weights (that are computed according to the number of times each distinct sequence appears in the dataset) and then add the clustering back to your original dataset. This can be made quite easily using the WeightedCluster library. The first appendix of the WeightedCluster Manual provides a step by step guide to do that (the procedure is also described on the webpage http://mephisto.unige.ch/weightedcluster).

Hope this helps.