I have an alias in .profile that clears the terminal when "c" is entered:
alias c='clear'
I want to call a KornShell (ksh) script every time I enter "c" in the terminal. What is the best way to accomplish this? I have googled and not been able to find anything.
An alias is essentially just a text replacement for what you actually type. Try modifying your alias to read
alias c='clear; myscript.ksh'