Breaking JavaScript execution when cookie is set

Is it possible to break javascript execution in browser developer tools always when a cookie is set (without setting JS breakpoints explicitly)?

document.cookie = '...';

This should work (run it in a console):

origDescriptor = Object.getOwnPropertyDescriptor(Document.prototype, 'cookie');
Object.defineProperty(document, 'cookie', {
  get() {
    return origDescriptor.get.call(this);
  },
  set(value) {
    debugger;
    return origDescriptor.set.call(this, value);
  },
  enumerable: true,
  configurable: true
});