Question title says it all really - a lot slower than VS2005, with a noticeable (0.5 sec) delay on each key press.
It makes stepping through code a pain.
As Joe90 says, SP1 might help; In addition, do you find that performance improves if you close unnecessary windows in the IDE? Do you have source control integration, and if so, what provider do you use (TFS/SourceSafe/etc.)