Google Chrome net::ERR_TOO_MANY_RETRIES

In Chrome, sometime request fails with Error: status (failed) net::ERR_TOO_MANY_RETIRES.

This happens randomly for 1 request while loading page with 80+ resource.

What could be possible reason for this error? I have attempted the following:

• Cleared the browser cache as well as set the option to disable cache in debugger
• The connection remains in Stalled state when the error occurs
• This happens in incognito mode too

The failing image in above screenshot is refereed in CSS as

background-image: url(/images/no-data-5-2x.png);

Interestingly, this works well with Firefox, and just fails in Chrome.

In a detail analysis, I checked the Chromium source code for ERR_TOO_MANY_RETIRES. And I found the following open bug reference in the file ./net/http/http_network_transaction.cc.

https://bugs.chromium.org/p/chromium/issues/detail?id=488043

The issue occurs in case of self signed certificate only. As a work around one can use valid certificate signed by CA for web application. Further details of the issue can be found by visiting the above URL.