What consideration would one take when designing a scalable web architecture

I know that one has to look at the queries for database, because when the database is small queries are not a problem. But when it becomes larger it could slow down the site.

Here's some things I would consider...

Handling Data:

• Returning as small a dataset as possible. This includes row counts & columns. For example, no select * from table....
• Data caching strategies

Web:

• File Caching.... AKA - HTML, images, javascript....
• Put JS at the bottom after DOM loads. Increases speed of page load.
• Put CSS at top.
• Session State - be careful with it's usage...
• Use CDNs when possible with local fallback....
• Minimize the postbacks / http requests
• GZip/compress your http
• compress your JS & CSS

Hardware setup:

• Load Balancing,proxies...