I have an application hosted on my local IIS (Windows 10).
From today I am not able to access the application in the browser (tried in Chrome, Browser and IE).
In the browser, I see 'ERR_CONNECTION_REFUSED'. (Same behaviour if I try to 'Browse Website' from IIS.) I tried browsing the Default Web Site on localhost and was a success.
I am able to ping the application from the command prompt.
There are no logs related to it in the IIS logs and the event viewer.
In registry,
at path: Computer\HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\HTTP\Parameters
it was having 2 values removed the second one, left the default one.
This fixed my issue.