pythonxmlsbml

How to read attributes for a sbml file with libsbml


I have a sbml model from Reactome, you can download it from https://reactome.org/content/detail/R-HSA-156581 and clicking sbml. For the <reaction>, some of it have attribute of <listOfModifiers>, and I'm trying to use libsbml or cobrapy for doing that.

My code read the sbml file, but how to get the attribute for <listOfModifiers>?

sbml_test_file = "./R-HSA-156581.sbml"

# Using the libSBML python API
# http://model.caltech.edu/software/libsbml/5.18.0/docs/formatted/python-api/libsbml-python-reading-files.html
reader = libsbml.SBMLReader()
document = reader.readSBML(sbml_test_file)
model = document.getModel()

Solution

  • The libsbml API is designed to directly mimic the structure of SBML itself. So, once you have the model, you get the reactions from the model, and once you have a reaction, you get the reaction's modifiers:

        import libsbml
        
        sbml_test_file = "R-HSA-156581.sbml"
        reader = libsbml.SBMLReader()
        document = reader.readSBML(sbml_test_file)
        model = document.getModel()
        for r in range(model.getNumReactions()):
            rxn = model.getReaction(r)
            for m in range(rxn.getNumModifiers()):
                mod = rxn.getModifier(m)
                print(mod.getId(), "in reaction", rxn.getId())