How to use KeyboardInterrupt with other exceptions?

I'm trying to use KeyboardInterrupt along with other errors but it doesn't seem to be working. (I have pyautogui and time imported already.) New to python btw.

while true
  try:
      x, y = pyautogui.locateCenterOnScreen('default.png')                                                 
      pyautogui.click(x, y)
      print (x, y)
      time.sleep(0.5)

  except ImageNotFoundException:
      print ("Nope nothing there. Try number:", tries)
      time.sleep(1)

  except KeyboardInterrupt:
      print("Manual shutdown activated...")
      time.sleep(1)
      break;

Here is a complete example of what you have with some time exaggerations:

import time

while True:
    print('outside try')
    time.sleep(1)  # interrupting here won't be caught
    try:
        print('inside try')  # interrupting here will be caught (small window)
        with open('nonexistent.file') as f:  # This will go to FileNotFoundError
            pass
    except FileNotFoundError:
        print('file not found')
        time.sleep(.5)  # interrupting here won't be caught
    except KeyboardInterrupt:
        break
    print('outside try')
    time.sleep(1)  # interrupting here won't be caught

print('exiting')

Wrap exactly the areas you expect to catch. Put the KeyboardInterrupt try around the whole while loop, and the FileNotFoundError try around opening the file:

try:
    while True:
        try:
            with open('nonexistent.file') as f:
                pass
        except FileNotFoundError:
            print('file not found')
except KeyboardInterrupt:
    print('exiting')