I'm struggling with HiDPI support of Android Studio 2.1.3 for Linux Mint. What I know it should be possible to enable Android Studio's HiDPI support by adding -Dhidpi=true flag to /opt/android-studio/bin/studio64.vmoptions Unfortunately it doesn't change anything on my machine, the UI is still very small.
I had the same problem, and I did not manage to "enable" hidpi for Android Studio.
Therefore, I run Android Studio like so:
$ xrandr --dpi 192; android-studio&
Or whatever you prefer instead of 192, of course.