Our production application pools (IIS 8.0-8-5, .Net 4.5 integrated pipeline) are set to recycle daily, this is unlikely to change in the short term.
Is there a way to prevent a DebugDiag (2.2.0.14) creating a dump at this time and blowing out our disk storage?
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Debug Diag is a troubleshooting tool, so it does not have too many options to configure. Generally speaking you should disable the rule as soon as possible.
But if you need to live it enabled, then your only chance is to set a limit on user dump count, and then manually remove useless dumps from the disk to clean up space. More information on user dump count configuration can be found in this article.