RFC call does not work on mac os using jco lib and java

SAP RFC call doesnot work on mac os platform. Same code run on windows. There is interesting things that If I connect to sap using with SAP GUI, I successfully call RFC on mac. I use sap official jco lib for connection.

My local machine config:

 SAP Java Connector runtime information

 Java Runtime:
    Operating System    : Mac OS X 10.12.4 for x86_64
    Java VM             : 1.8.0_121 Oracle Corporation
    Default charset     : UTF-8

 Versions:
    JCo API             : 3.0.16 (2016-12-06)
    JCo middleware      : JavaRfc 2.2.19
    JCo library         : 721.800

 Library Paths:
    Path to JCo archive : /Users/**/sapcorejco/lib/sapjco3.jar
    Path to JCo library : /Users/**/lib/darwinintel64/libsapjco3.jnilib

My erorr is

ERROR [hybrisHTTP10] [DefaultSAPRFCDestinationService] com.sap.conn.jco.JCoException: (102) JCO_ERROR_COMMUNICATION: Initialization of destination SQ2 failed: Connect to SAP gateway failed

Detail:

LOCATION    CPIC (TCP/IP) on local host
ERROR       timeout occured

I think, main problem related to MAC OS, because same code run in windows machine. Maybe we missing some library it come from sap gui? Is there anyone faced this issue?

I finally resolved problem. Problem related VPN applications. I use for vpn Tunnelblick application. We use side to side vpn and tunnelblick default version doesnot fully support. We changed version of tunnelblick solved all problems.Tunnelblick default version: 2.4.6 but I use 2.3.18 for side to side vpn.