Create background for a 3D and 2D plots

Can someone help me create a layout for plots with the following structure:

A   CD
A/B EF
B   GH

where A,B are 3D plots (fig.add_subplot(241, projection='3d')) and C,D,E,F,G,H are regular 2D plots. A/B represents a shared space where half of plot A and half of plot B appear.

You could use a subplot_mosaic:

f, grid = plt.subplot_mosaic('''\
ACD
ACD
AEF
BEF
BGH
BGH''', per_subplot_kw={('A', 'B'): {'projection': '3d'}} )

plt.tight_layout()

Then plot on grid['A']/grid['B']/grid['C']/...

Output:

If you need a more flexible, play with the gridspec:

f, grid = plt.subplot_mosaic('''\
ACD
ACD
AEF
BEF
BGH
BGH''', per_subplot_kw={('A', 'B'): {'projection': '3d'}},
        gridspec_kw={'width_ratios':[3, 1, 1],
                     'height_ratios':[3, 1, 1, 1, 1, 1],
                    })

plt.tight_layout()

Output: